Antenatal Risk Assessment

FIRST & SECOND TRIMESTER ANTENATAL RISK ASSESSMENT packages or OSCAR (One-stop Clinic For Assessment of Risk for Fetal Anomalies)

Most babies are normal but a few may be born with major physical or mental disability due to chromosome abnormalities. The most common of such abnormalities is Down Syndrome. Diagnostic tests such as amniocentesis or chorionic villus sampling are the only way to be certain of chromosome abnormalities. However, these tests are associated with a risk of miscarriage. Fortunately, screening tests are available to determine the chance of the baby having specific chromosomal abnormalities like Trisomy 21 (Down Syndrome), Trisomy 18 (Edward's Syndrome) and Trisomy 13 (Patau Syndrome). They are designed to help couples decide whether they wish to proceed to invasive diagnostic tests.

First Trimester Screening (FTS)

FTS combines maternal blood testing with an ultrasound evaluation of the fetus. This is performed between 11-14 weeks of pregnancy and the detection rate for chromosomal abnormalities is 90%.

Second Trimester Screening

Maternal serum screening is a blood test conducted between 15 and 20 weeks of pregnancy to aid in the risk assessment of Down Syndrome. The blood test measures the amount of human chorionic gonadotrophin (hCG) and alpha-fetoprotein (AFP) which are produced by the fetus and the placenta. These results are combined with the mother's age to calculate the chance of having a Down Syndrome baby.


NIPT is a new test to screen for genetic conditions such as Down syndrome and certain other genetic disorders. There is no risk to the mother and fetus as it involves analyzing a sample of the motherís blood for cell-free fetal DNA.

Clinic Operating Hours:
Monday - Friday: 9am - 1pm, 2pm - 7pm
Saturday: 9am - 1pm
Closed on Sunday & Public Holidays
321 Clementi (WE Cinema Mall)
Block 321 #01-05, Clementi Ave 3
Singapore 129905
Tel: 6873 3383
Fax: 6873 3373
After office: 6535 8833

Email: gynaemdclementi@singnet.com.sg
Website: www.GynaeMDClementi.com.sg